Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.76 |
| ▸ | MAPT | P10636 | 7/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.76 |
| ▸ | SLC15A2 | Q16348 | 3/20 | 0.76 |
| ▸ | HPGD | P15428 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.76 |
| ▸ | BLM | P54132 | 2/20 | 0.76 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.76 |
| ▸ | HTR2B | P41595 | 1/20 | 0.76 |
| ▸ | MEN1 | O00255 | 4/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | ESR1 | P03372 | 1/20 | 0.68 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.68 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574032 | 1.00 | HSD17B10 (0.76) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| SCHEMBL11573283 | 0.89 | MAPT (0.79) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| SCHEMBL11573271 | 0.89 | MAPT (0.79) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cefsumide SCHEMBL11217305 | 0.89 | HSD17B10 (0.75) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cefsumide SCHEMBL30688405 | 0.89 | HSD17B10 (0.75) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cefsumide SCHEMBL612272 | 0.89 | HSD17B10 (0.75) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL10925361 | 0.87 | HSD17B10 (1.00) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL11985597 | 0.87 | HSD17B10 (1.00) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL8481524 | 0.87 | HSD17B10 (1.00) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 | |
| Cephalexin Anhydrous SCHEMBL20703090 | 0.87 | HSD17B10 (1.00) | HSD17B10MAPTALDH1A1KMT2ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | claimed |
| US-4091227-A | ANTIBACTERIAL AGENTS | SMITHKLINE CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |
| US-4067978-A | ANTIBACTERIAL | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4067976-A | BACTERICIDES | SMITHKLINE CORPORATION (US) | 1978-01-10 | — | — | US | disclosed |
| US-4007173-A | BACTERICIDE | SMITHKLINE CORPORATION (US) | 1977-02-08 | — | — | US | disclosed |