Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | CA12 | O43570 | 6/20 | 0.64 |
| ▸ | CA2 | P00918 | 6/20 | 0.64 |
| ▸ | CA9 | Q16790 | 5/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 6/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28232345 | 0.91 | TSHR (0.62) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL27537010 | 0.88 | TSHR (0.69) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL11977377 | 0.86 | TSHR (0.67) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL460754 | 0.83 | TSHR (1.00) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL18756245 | 0.82 | TSHR (0.67) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL14580319 | 0.82 | TSHR (0.67) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL13995849 | 0.79 | TSHR (0.62) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL13995732 | 0.79 | TSHR (0.62) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL12996041 | 0.79 | TSHR (0.62) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL11130325 | 0.79 | TSHR (0.56) | TSHRCYP2D6HIF1ACA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7238339-B2 | Bifunctional chelating compounds containing hydroxamic acid residues | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2007-07-03 | — | — | US | disclosed |
| US-7238339-B2 | Bifunctional chelating compounds containing hydroxamic acid residues | DRAXIS SPECIALTY PHARMACEUTICALS INC. (CA) | 2007-07-03 | — | — | US | disclosed |
| US-4116991-A | HYDROXY-CONTAINING AGENTS FOR CHELATING METAL IONS AND A PROCESS FOR PREPARING SAME | MANUFACTURE DE PRODUITS CHIMIQUES PROTEX (FR) | 1978-09-26 | — | — | US | disclosed |