SCHEMBL11575259

SCHEMBL11575259

COc1cccc(=O)c(O)c1OC

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 3/20 0.60
HDAC2 Q92769 3/20 0.60
HDAC8 Q9BY41 3/20 0.60
MAPT P10636 4/20 0.54
TP53 P04637 2/20 0.52
ALOX15 P16050 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
CYP3A4 P08684 1/20 0.52
HPGD P15428 1/20 0.52
ALOX12 P18054 1/20 0.52
MAPK1 P28482 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
TLR2 O60603 1/20 0.47
ERN1 O75460 1/20 0.47
TLR1 Q15399 1/20 0.47
TLR6 Q9Y2C9 1/20 0.47
NFE2L2 Q16236 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5693313 0.81 MAPT (0.58) HDAC4HDAC2HDAC8MAPTTP53
SCHEMBL11442190 0.79 CA1 (0.55) HDAC4HDAC2HDAC8MAPTTP53
SCHEMBL25434306 0.75 CA1 (0.61) MAPTTP53ALOX15KDM4EALDH1A1
SCHEMBL27753904 0.75 CA1 (0.61) MAPTTP53ALOX15KDM4EALDH1A1
SCHEMBL151213 0.75 CA1 (0.61) MAPTTP53ALOX15KDM4EALDH1A1
SCHEMBL186826 0.74 MAPT (0.67) MAPTTP53ALOX15KDM4EALDH1A1
SCHEMBL1402474 0.73 MAPT (0.61) HDAC4HDAC2HDAC8MAPTTP53
Formaldehyde SCHEMBL28092618 0.73 SMN1; SMN2 (0.54) MAPTTP53ALOX15KDM4EALDH1A1
SCHEMBL10437519 0.73 HDAC4 (0.49) HDAC4HDAC2HDAC8MAPTTP53
Syringol SCHEMBL156388 0.73 KDM4E (0.80) MAPTTP53ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118027794-A Quick-drying type double-component polyurethane water-based paint 固克节能科技股份有限公司 2024-05-14 CN claimed
CN-116535958-A Quick-drying type double-component polyurethane water-based paint and preparation method thereof 龙牌涂料(北京)有限公司 2023-08-04 CN claimed
JP-53135954-A None JP disclosed
CN-118027794-A Quick-drying type double-component polyurethane water-based paint 固克节能科技股份有限公司 2024-05-14 CN disclosed
CN-116535958-A Quick-drying type double-component polyurethane water-based paint and preparation method thereof 龙牌涂料(北京)有限公司 2023-08-04 CN disclosed
JP-S53135954-A 3,4-DIMETHOXYTROPOLONE AND ITS PREPARATION KYOWA HAKKO KOGYO CO LTD 1978-11-28 JP disclosed