Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 6/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | THPO | P40225 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.44 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.43 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11253160 | 0.87 | MAPT (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL11350210 | 0.78 | CACNA1C (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL10352579 | 0.76 | MEN1 (0.61) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL11324920 | 0.75 | CACNA1F (0.53) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL11579185 | 0.75 | CACNA1C (0.51) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL6425850 | 0.74 | MEN1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL11364501 | 0.74 | PDE1C (0.69) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL10974743 | 0.74 | MEN1 (0.67) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL11330354 | 0.74 | MEN1 (0.52) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 | |
| SCHEMBL10912016 | 0.74 | CACNA1C (0.60) | CYP1A2CYP3A4CYP2C9CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0001108-A1 | 1,4-Dihydropyridazines, process for their preparation and their use in pharmaceuticals | BAYER AG (DE) | 1979-03-21 | — | — | EP | disclosed |