Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | LPL | P06858 | 1/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL27925242 | 0.82 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| Hydrogen Sulfide SCHEMBL29290777 | 0.82 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL36295 | 0.78 | TP53 (0.67) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL14025181 | 0.78 | TP53 (0.46) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL10657323 | 0.76 | TP53 (0.43) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL27756675 | 0.75 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| Ammonia Solution, Strong SCHEMBL27293386 | 0.75 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL7542835 | 0.75 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL31498555 | 0.75 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 | |
| SCHEMBL28166306 | 0.75 | TP53 (0.62) | ALDH1A1TP53SMN1; SMN2TAAR1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129699-A | QUATERNARY AMMONIUM SALT CATALYST | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1978-12-12 | — | — | US | disclosed |