Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 3/20 | 0.49 |
| ▸ | FNTB | P49356 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.48 |
| ▸ | SQLE | Q14534 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11574425 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL11574815 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL12281204 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL11575551 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL11575899 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL1564345 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL6061058 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL10297988 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL10490785 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A | |
| SCHEMBL12457084 | 1.00 | KDM4E (0.55) | KDM4EATMALDH1A1ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-52144614-A | — | — | None | — | — | JP | disclosed |
| US-4130659-A | Polyprenyl carboxylic acid compound and hypotensive agent containing it as active ingredient | EISAI CO., LTD. (JP) | 1978-12-19 | — | — | US | disclosed |
| US-4107193-A | HYPOTENSIVE | EISAI CO., LTD. (JP) | 1978-08-15 | — | — | US | disclosed |
| JP-S52144614-A | POLYPRENYL CARBOXYLIC ACID COMPOUNDS AND HYPO-TENSOR CONTAINING SAME | EISAI CO LTD | 1977-12-02 | — | — | JP | disclosed |