Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 10/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.49 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.49 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11577183 | 0.89 | P2RX4 (0.49) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| Hydrochloric Acid SCHEMBL11574541 | 0.88 | P2RX4 (0.48) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| SCHEMBL13875724 | 0.78 | GRIN1 (0.76) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| SCHEMBL15920342 | 0.72 | P2RX4 (0.67) | P2RX4GRIN1GRIN2AGRIN2BBCHE | |
| SCHEMBL11770681 | 0.72 | P2RX4 (0.71) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| SCHEMBL11727362 | 0.71 | P2RX4 (0.74) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| SCHEMBL11721455 | 0.70 | GRIN1 (0.66) | P2RX4GRIN1GRIN2AGRIN2BASAH1 | |
| SCHEMBL11039708 | 0.69 | GRIN1 (0.92) | P2RX4GRIN1GRIN2AGRIN2B | |
| SCHEMBL13051502 | 0.69 | BCHE (0.68) | P2RX4GRIN1GRIN2AGRIN2BBCHE | |
| SCHEMBL11721111 | 0.69 | P2RX4 (0.71) | P2RX4GRIN1GRIN2AGRIN2BBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4076707-A | N-(2-hexamethyleniminoethyl)-5H-dibenz[b,f]-azepine-5-carboxamides and quaternary ammonium derivatives thereof | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | claimed |
| US-4076707-A | N-(2-hexamethyleniminoethyl)-5H-dibenz[b,f]-azepine-5-carboxamides and quaternary ammonium derivatives thereof | G. D. SEARLE & CO. (US) | 1978-02-28 | — | — | US | disclosed |