Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.41 |
| ▸ | HMGCR | P04035 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8582771 | 1.00 | TSHR (0.53) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL3695352 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL14759610 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL14759630 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL14760261 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL3697613 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL6745588 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL10631303 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL11579416 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 | |
| SCHEMBL3199000 | 0.97 | TSHR (0.57) | TSHRTHRBPTPN7HMGCRDNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129586-A | Peroxide free radical initiators containing ultraviolet light stabilizing groups | PENNWALT CORPORATION (US) | 1978-12-12 | — | — | US | disclosed |
| US-4055714-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-10-25 | — | — | US | disclosed |
| US-4045427-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4045426-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1977-08-30 | — | — | US | disclosed |
| US-4042773-A | REACTION WITH POLYMERS | PENNWALT CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3956269-A | POLYMERIZATION CATALYSTS | PENNWALT CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |