Phthalic Acid

Phthalic Acid

SCHEMBL11577907

O=C(O)c1ccccc1C(=O)O.O=C(c1ccccc1)c1ccccc1O

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 3/20 0.76
ALDH1A1 P00352 4/20 0.68
KDM4E B2RXH2 2/20 0.68
CA12 O43570 1/20 0.68
CA1 P00915 1/20 0.68
CA2 P00918 1/20 0.68
HMGB1 P09429 1/20 0.68
HPGD P15428 1/20 0.68
CA4 P22748 1/20 0.68
CA6 P23280 1/20 0.68
CA7 P43166 1/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
CA9 Q16790 1/20 0.68
NAPRT Q6XQN6 1/20 0.68
CA14 Q9ULX7 1/20 0.68
LIG1 P18858 1/20 0.68
CDC25B P30305 2/20 0.60
ATM Q13315 1/20 0.60
ALOX15 P16050 1/20 0.58
GAA P10253 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129808 0.94 LIG1 (0.76) AKR1C3ALDH1A1KDM4ECA12CA1
SCHEMBL29390505 0.94 LIG1 (0.76) AKR1C3ALDH1A1KDM4ECA12CA1
Benzene SCHEMBL6034371 0.94 LIG1 (0.76) AKR1C3ALDH1A1KDM4ECA12CA1
SCHEMBL36215 0.94 LIG1 (0.76) AKR1C3ALDH1A1KDM4ECA12CA1
Ammonia Solution, Strong SCHEMBL28945185 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1
Bicarbonate SCHEMBL376894 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1
Bicarbonate SCHEMBL3979276 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1
SCHEMBL9717050 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1
SCHEMBL29254155 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1
SCHEMBL11308720 0.91 LIG1 (0.73) AKR1C3ALDH1A1KDM4ECA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4129586-A Peroxide free radical initiators containing ultraviolet light stabilizing groups PENNWALT CORPORATION (US) 1978-12-12 US disclosed
US-4055714-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-10-25 US disclosed
US-4045426-A POLYMERIZATION CATALYSTS PENNWALT CORPORATION (US) 1977-08-30 US disclosed