Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.43 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.43 |
| ▸ | FGR | P09769 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11582997 | 0.87 | ADORA2A (0.54) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL6366580 | 0.82 | ADORA2A (0.58) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL11579534 | 0.81 | MAPT (0.75) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL1683323 | 0.80 | ADORA2A (0.65) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL10339614 | 0.78 | MAPT (0.64) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL11581942 | 0.77 | MAPT (0.84) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL11421896 | 0.75 | MAPT (0.69) | ADORA2AMAPTMAPK1KDM4ENSD2 | |
| SCHEMBL29944895 | 0.75 | ADORA2A (0.86) | ADORA2AMAPTMAPK1PTPRCMAOA | |
| SCHEMBL64318 | 0.75 | ADORA2A (0.86) | ADORA2AMAPTMAPK1PTPRCMAOA | |
| SCHEMBL11583208 | 0.75 | KDM4E (0.55) | ADORA2AMAPTMAPK1KDM4ENSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126626-A | DYES, POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1978-11-21 | — | — | US | disclosed |