Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 4/20 | 0.45 |
| ▸ | PHF8 | Q9UPP1 | 4/20 | 0.45 |
| ▸ | KDM2A | Q9Y2K7 | 4/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11580528 | 0.91 | KDM5A (0.40) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL4943340 | 0.85 | METAP1 (0.46) | METAP1 | |
| SCHEMBL10685188 | 0.84 | METAP1 (0.49) | METAP1MEN1KMT2AEPHX1 | |
| SCHEMBL2703035 | 0.83 | KDM5A (0.54) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL2125598 | 0.81 | KDM5A (0.51) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL11626601 | 0.81 | KDM5A (0.41) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL11669537 | 0.79 | KDM5A (0.53) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL27883531 | 0.77 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL9967863 | 0.77 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CKDM4A | |
| SCHEMBL13267846 | 0.75 | KDM5A (0.50) | KDM5APHF8KDM2AKDM4CKDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152527-A | 15-Substituted-ω-pentanorprostaglandins | PFIZER INC. (US) | 1979-05-01 | — | — | US | disclosed |