Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.30 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178549 | 0.85 | EP300 (0.47) | GRIK1TSHREP300F7F3 | |
| SCHEMBL1657191 | 0.78 | GRIK1 (0.35) | GRIK1TSHRALDH1A1EP300SPHK1 | |
| SCHEMBL1657189 | 0.78 | GRIK1 (0.35) | GRIK1TSHRALDH1A1EP300SPHK1 | |
| SCHEMBL7564265 | 0.75 | EP300 (0.50) | GRIK1TSHREP300KMT2AF7 | |
| SCHEMBL7564268 | 0.75 | EP300 (0.50) | GRIK1TSHREP300KMT2AF7 | |
| SCHEMBL18250686 | 0.73 | GRIK1 (0.33) | GRIK1TSHRALDH1A1EP300 | |
| SCHEMBL28777510 | 0.73 | EP300 (0.48) | GRIK1TSHREP300F7F3 | |
| SCHEMBL7558849 | 0.70 | EP300 (0.46) | GRIK1TSHREP300F7F3 | |
| SCHEMBL7558847 | 0.70 | EP300 (0.46) | GRIK1TSHREP300F7F3 | |
| SCHEMBL12987113 | 0.70 | GRIK1 (0.36) | GRIK1TSHRALDH1A1EP300MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098881-A | COMPOSITIONS TO CONTROL THE CHRONIC EFFECTS OF EXPOSURE TO SUNLIGHT COMPRISING CONJUGATED DIENES | THE PROCTER & GAMBLE COMPANY (US) | 1978-07-04 | — | — | US | disclosed |