Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | FBP1 | P09467 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11593456 | 0.92 | MEN1 (0.51) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11149199 | 0.92 | MAPT (0.55) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL10796950 | 0.91 | MAPK1 (0.49) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11137496 | 0.89 | MEN1 (0.49) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11587443 | 0.88 | MEN1 (0.54) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11587743 | 0.88 | MEN1 (0.48) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11232334 | 0.88 | MAPT (0.59) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL10527347 | 0.88 | MAPT (0.56) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11587093 | 0.88 | MEN1 (0.48) | MAPK1MEN1KMT2AKIF11HSP90AA1 | |
| SCHEMBL11586472 | 0.88 | MEN1 (0.44) | MAPK1MEN1KMT2AKIF11HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | claimed |
| US-4084004-A | Rodenticidal use of diphenylamines | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |