Benzonitrile

Benzonitrile

SCHEMBL11596153

C1CCCCC1.N#Cc1ccccc1

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.82
MAOB P27338 5/20 0.52
MAOA P21397 4/20 0.52
APP P05067 1/20 0.45
ALDH1A1 P00352 2/20 0.43
CYP2A6 P11509 2/20 0.43
CA12 O43570 1/20 0.43
CA2 P00918 1/20 0.43
CA3 P07451 1/20 0.43
CA6 P23280 1/20 0.43
CA9 Q16790 1/20 0.43
CA14 Q9ULX7 1/20 0.43
OPRD1 P41143 1/20 0.41
MAPT P10636 2/20 0.41
HDAC8 Q9BY41 2/20 0.40
LOXL2 Q9Y4K0 1/20 0.39
MMP3 P08254 1/20 0.39
ENPP2 Q13822 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzonitrile SCHEMBL9464940 0.91 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL2153738 0.91 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL27793280 0.91 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL6640 0.91
Benzonitrile SCHEMBL21752925 0.91
Benzonitrile SCHEMBL27363057 0.91 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL11044747 0.91
Benzonitrile SCHEMBL30929383 0.91 TSHR (1.00) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL25253064 0.88 TSHR (0.93) TSHRMAOBMAOAAPPALDH1A1
Benzonitrile SCHEMBL11774035 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-54078380-A None JP disclosed
JP-54078381-A None JP disclosed
CN-114364737-B Composition for forming heat conductive material, heat conductive sheet, and device with heat conductive layer 富士胶片株式会社 2024-05-07 CN disclosed
CN-116804777-A Optical laminate and circularly polarizing plate 日东电工株式会社 2023-09-26 CN disclosed
JP-S5478381-A LIQUID CRYSTAL COMPOSITION ASAHI GLASS CO LTD 1979-06-22 JP disclosed
JP-S5478380-A LIQUID CRYSTAL COMPOSITION ASAHI GLASS CO LTD 1979-06-22 JP disclosed