Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.56 |
| ▸ | PPARD | Q03181 | 5/20 | 0.53 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598101 | 0.84 | PPARG (0.51) | PPARGPPARAKDM4E | |
| SCHEMBL11597904 | 0.82 | PPARG (0.53) | PPARGFFAR1PPARA | |
| SCHEMBL11596781 | 0.81 | PPARG (0.52) | PPARGPPARDPPARAKDM4E | |
| SCHEMBL11596766 | 0.81 | PPARG (0.55) | PPARGPPARDPPARAKDM4E | |
| SCHEMBL11595480 | 0.80 | PPARG (0.50) | PPARGPPARAKDM4E | |
| SCHEMBL11574826 | 0.79 | PPARG (0.57) | PPARGPPARAKDM4E | |
| SCHEMBL11596938 | 0.79 | PPARG (0.53) | PPARGPPARA | |
| SCHEMBL2495708 | 0.79 | PPARG (0.61) | PPARGPPARAKDM4ESLC22A12 | |
| SCHEMBL11752505 | 0.79 | PPARG (0.67) | PPARGPPARA | |
| SCHEMBL14889080 | 0.79 | PPARG (0.67) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4125732-A | HYPOLIPIDEMIC | AMERICAN CYANAMID COMPANY (US) | 1978-11-14 | — | — | US | disclosed |