Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21905419 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL11600457 | 0.81 | TSHR (0.50) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL17890135 | 0.80 | TSHR (0.76) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL16448 | 0.80 | — | — | |
| SCHEMBL28192845 | 0.80 | TSHR (1.00) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL689966 | 0.79 | TSHR (0.62) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL268430 | 0.79 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL2201804 | 0.79 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL268127 | 0.79 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL30589890 | 0.79 | TSHR (0.73) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4071508-A | SIMULTANEOUS POLYMERIZATION | PLASTOMEDICAL SCIENCES, INC. (US) | 1978-01-31 | — | — | US | disclosed |
| US-4036788-A | Anionic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-07-19 | — | — | US | disclosed |