Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 2/20 | 0.60 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.57 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD3 | P35462 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | FNTA | P49354 | 1/20 | 0.47 |
| ▸ | FNTB | P49356 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HTR2C | P28335 | 3/20 | 0.47 |
| ▸ | HTR2B | P41595 | 3/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600894 | 0.92 | PTAFR (0.63) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11602084 | 0.90 | DRD3 (0.65) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL9718729 | 0.88 | SETD7 (0.55) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11601728 | 0.87 | KCNH2 (0.53) | PTAFRSETD7DRD2DRD3MAPT | |
| Hydrochloric Acid SCHEMBL9718758 | 0.87 | SETD7 (0.54) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11600303 | 0.86 | PTAFR (0.46) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11600654 | 0.86 | FNTA (0.54) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11601095 | 0.86 | SETD7 (0.67) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL11600139 | 0.85 | SETD7 (0.58) | PTAFRSETD7DRD2DRD3MEN1 | |
| SCHEMBL9718809 | 0.84 | SETD7 (0.54) | PTAFRSETD7DRD2DRD3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | claimed |
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |