SCHEMBL11599797

SCHEMBL11599797

CCCCCCC=C1CC2C=CC1C2

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.51
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
PPARG P37231 2/20 0.31
TSHR P16473 3/20 0.31
TYR P14679 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11598078 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11651749 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11600277 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11599793 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11598075 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11598932 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11598754 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11598934 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11600274 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG
SCHEMBL11598750 1.00 HSD17B10 (0.51) HSD17B10NFKB1NFKB2RELAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4131577-A POLYOLEFINS, REINFORCEMENT, BUTADIENE AND AN ACRYLIC ESTER TEXACO INC. (US) 1978-12-26 US disclosed
US-4107110-A GLASS, ASBESTOS, OR CELLULOSE FIBER COATED WITH UNSATURATED POLYHYDROCARBON-ACRYLATE GRAFT COPOLYMER TEXACO INC. (US) 1978-08-15 US disclosed
US-4065521-A Acrylate-butadiene graft copolymers and reinforced plastic compositions containing such copolymers TEXACO INC. (US) 1977-12-27 US disclosed
US-4026809-A Lubricating compositions containing methacrylate ester graft copolymers as useful viscosity index improvers TEXACO INC. (US) 1977-05-31 US disclosed