Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.41 |
| ▸ | DRD4 | P21917 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | HRH2 | P25021 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602054 | 0.94 | SETD7 (0.50) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11600100 | 0.90 | SETD7 (0.61) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11602831 | 0.88 | SETD7 (0.51) | SETD7CYP3A4MEN1KMT2ALMNA | |
| SCHEMBL11600671 | 0.88 | MEN1 (0.41) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11599909 | 0.87 | SETD7 (0.50) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11602448 | 0.87 | SETD7 (0.47) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11576476 | 0.85 | SETD7 (0.56) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11574857 | 0.85 | SETD7 (0.52) | SETD7CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL11600176 | 0.85 | SETD7 (0.48) | SETD7MEN1KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL11600294 | 0.85 | SETD7 (0.48) | SETD7CYP1A2CYP3A4CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |