Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390053 | 0.79 | ELANE (0.58) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL28665285 | 0.79 | KMT2A (0.60) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL26804303 | 0.78 | KMT2A (0.55) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11052292 | 0.77 | MAPT (0.58) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL26802703 | 0.76 | KMT2A (0.58) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL10499265 | 0.76 | CA12 (0.41) | KMT2ASMN1; SMN2RAB9AALDH1A1MAPT | |
| SCHEMBL10690444 | 0.76 | PARP10 (0.57) | KMT2AALDH1A1 | |
| SCHEMBL8051337 | 0.76 | SMN1; SMN2 (0.70) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL23802411 | 0.75 | KMT2A (0.53) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL20278607 | 0.75 | KMT2A (0.60) | KMT2ASMN1; SMN2RAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108949-A | 6-Hydroxy (alkoxy) phenylthiomethylene di(organophosphorus) compounds and process for making same | MONSANTO COMPANY (US) | 1978-08-22 | — | — | US | disclosed |
| US-4071584-A | Hydroxyphenylthiophosphoranylidene organophosphorus compounds | MONSANTO COMPANY (US) | 1978-01-31 | — | — | US | disclosed |