SCHEMBL1160198

SCHEMBL1160198

NCC1CCCC(CO)C1

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.52
CYP2D6 P10635 2/20 0.35
ESR1 P03372 5/20 0.33
ESR2 Q92731 5/20 0.33
PLG P00747 1/20 0.33
PLAT P00750 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C9 P11712 1/20 0.33
ALOX5 P09917 1/20 0.31
NCF1 P14598 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24906805 0.90
SCHEMBL31243360 0.90
Hydrochloric Acid SCHEMBL31313029 0.87 EPHX2 (0.54) EPHX2ESR1ESR2PLGPLAT
SCHEMBL674423 0.87 ESR1 (0.39) EPHX2CYP2D6ESR1ESR2CYP3A4
SCHEMBL7135021 0.87 EPHX2 (0.39) EPHX2CYP2D6PLGPLATLMNA
SCHEMBL1703647 0.87 EPHX2 (0.39) EPHX2CYP2D6PLGPLATLMNA
SCHEMBL1703645 0.87 EPHX2 (0.39) EPHX2CYP2D6PLGPLATLMNA
SCHEMBL674422 0.87 ESR1 (0.39) EPHX2CYP2D6ESR1ESR2CYP3A4
SCHEMBL26661 0.87 EPHX2 (0.39) EPHX2CYP2D6PLGPLATLMNA
SCHEMBL63504 0.87 ESR1 (0.39) EPHX2CYP2D6ESR1ESR2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1043376-B1 Use of anionic or cationic plasticizers with sulfonated polyesters in hot melt formulations NAT STARCH CHEM INVEST (US) 2004-12-08 EP claimed
EP-1043376-A2 Use of anionic or cationic plasticizers with sulfonated polyesters in hot melt formulations National Starch and Chemical Investment Holding Corporation (US) 2000-10-11 EP claimed
WO-2023069884-A1 KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE IMAGO BIOSCIENCES, INC. (US) 2023-04-27 WO disclosed
CN-106966908-B Process for improving the catalytic activity of catalyst systems for reductive amination of aliphatic cyanoaldehydes to aliphatic diamines 陶氏环球技术有限责任公司 2020-07-31 CN disclosed
EP-2459516-B1 A PROCESS FOR PREPARING AND SEPARATING ONE OR MORE ALIPHATIC DIAMINES FROM REDUCTIVE AMINATION REACTION SOLVENTS AND IMPURITIES DOW GLOBAL TECHNOLOGIES LLC (US) 2017-08-23 EP disclosed
EP-2459514-B1 CYCLOALIPHATIC DIAMINES AND METHOD OF MAKING THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2017-07-19 EP disclosed
CN-102482198-B The method that reproducibility aminating reaction solvent is separated with one or more aliphatic diamines with impurity 陶氏环球技术有限责任公司 2016-06-15 CN disclosed
US-9233908-B2 Cycloaliphatic diamines and method of making the same DOW GLOBAL TECHNOLOGIES LLC (US) 2016-01-12 US disclosed
US-9187403-B2 Process for separating one or more aliphatic diamines from reductive amination reaction solvents and impurities DOW GLOBAL TECHNOLOGIES LLC (US) 2015-11-17 US disclosed
EP-2459515-B1 PROCESS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2015-08-19 EP disclosed
EP-2488482-B1 PROCESS FOR IMPROVING THE CATALYTIC ACTIVITY OF CATALYST SYSTEMS FOR REDUCTIVE AMINATION OF ALIPHATIC CYANOALDEHYDES TO ALIPHATIC DIAMINES DOW GLOBAL TECHNOLOGIES LLC (US) 2015-08-19 EP disclosed
EP-0761795-B1 Hot melt adhesives based on sulfonated polyesters NAT STARCH CHEM INVEST (US) 2000-05-31 EP disclosed
EP-0960148-A4 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORP (US) 2000-03-08 EP disclosed
US-6001910-A COPOLYMER WITH SULFODIACIDS, DICARBOXYLIC ACIDS AND GLYCOLS AND DIAMINE GLYCOLS OR HYDROXY CARBOXYLIC ACIDS WITH PLASTICIZERS, TACKIFIERS, ANTIOXIDANTS AND WAX DILUENTS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1999-12-14 US disclosed
EP-0960148-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM United States Surgical Corporation (US) 1999-12-01 EP disclosed
US-5902875-A Polyesteramide, its preparation and surgical devices fabricated therefrom UNITED STATES SURGICAL CORPORATION (US) 1999-05-11 US disclosed
WO-1998032779-A1 POLYESTERAMIDE, ITS PREPARATION AND SURGICAL DEVICES FABRICATED THEREFROM UNITED STATES SURGICAL CORPORATION (US) 1998-07-30 WO disclosed
US-5750605-A Hot melt adhesives based on sulfonated polyesters NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 1998-05-12 US disclosed
EP-0761795-A2 Hot melt adhesives based on sulfonated polyesters National Starch and Chemical Investment Holding Corporation (US) 1997-03-12 EP disclosed
US-4855397-A Polyesteramide from amino alcohol with improved gas barrier properties EASTMAN KODAK COMPANY (US) 1989-08-08 US disclosed