Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11605682 | 0.88 | MAPK13 (0.51) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL11606334 | 0.86 | MEN1 (0.59) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL11605165 | 0.86 | MEN1 (0.59) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL11602835 | 0.86 | MEN1 (0.58) | RAB9AMEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL11601179 | 0.86 | MEN1 (0.58) | RAB9AMEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL8088894 | 0.86 | MEN1 (0.58) | RAB9AMEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL11786449 | 0.86 | MEN1 (0.58) | RAB9AMEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL4008235 | 0.86 | MEN1 (0.58) | RAB9AMEN1NPC1KMT2AL3MBTL1 | |
| SCHEMBL11605556 | 0.84 | MAPK13 (0.62) | MAPK13MAPK12MAPK11MAPK14RAB9A | |
| SCHEMBL10791991 | 0.83 | MAPT (0.64) | RAB9AMEN1NPC1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4128396-A | Process for the improvement of dyeing properties of pigments of the anilino and arylmercapto anthraquinone series | CIBA-GEIGY CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |
| US-3975410-A | Process for the manufacture of halogen-containing anthraquinoidal compounds, their use and new halogen-containing anthraquinoidal compounds | CIBA-GEIGY CORPORATION (US) | 1976-08-17 | — | — | US | disclosed |