Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | GMNN | O75496 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11112682 | 0.87 | MEN1 (0.52) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11113992 | 0.87 | MEN1 (0.52) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11117547 | 0.85 | GRM2 (0.56) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11213078 | 0.83 | GRM2 (0.55) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11114148 | 0.83 | GRM2 (0.55) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11116330 | 0.83 | HSD17B10 (0.53) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11114354 | 0.83 | KDM4E (0.43) | HSD17B10MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL11115126 | 0.82 | CYP3A4 (0.50) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11602516 | 0.82 | MEN1 (0.52) | HSD17B10MEN1KMT2ATSHRCYP3A4 | |
| SCHEMBL11603610 | 0.82 | HSD17B10 (0.54) | HSD17B10MEN1KMT2ATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4070539-A | DIURETICS, SALURETICS | MERCK & CO., INC. (US) | 1978-01-24 | — | — | US | disclosed |