Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606580 | 1.00 | APEX1 (0.50) | APEX1S1PR3ALDH1A1KMT2AGLA | |
| SCHEMBL11603218 | 1.00 | APEX1 (0.50) | APEX1S1PR3ALDH1A1KMT2AGLA | |
| SCHEMBL5720587 | 0.86 | APEX1 (0.56) | APEX1ALDH1A1NT5ELMNAHPGD | |
| SCHEMBL8372159 | 0.82 | APEX1 (0.53) | APEX1ALDH1A1NT5ELMNAL3MBTL1 | |
| SCHEMBL16706094 | 0.81 | APEX1 (0.54) | APEX1ALDH1A1GLANT5ELMNA | |
| SCHEMBL5720562 | 0.80 | APEX1 (0.61) | APEX1ALDH1A1KMT2ANT5ELMNA | |
| SCHEMBL11593569 | 0.80 | APEX1 (0.55) | APEX1ALDH1A1NT5ELMNATDP1 | |
| SCHEMBL10876157 | 0.78 | APEX1 (0.49) | APEX1ALDH1A1NT5EMAPTPKM | |
| SCHEMBL8113776 | 0.76 | APEX1 (0.60) | APEX1ALDH1A1KMT2ANT5ELMNA | |
| SCHEMBL11650870 | 0.75 | APEX1 (0.49) | APEX1ALDH1A1NT5EMAPTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4080322-A | WATER SOLUBLE DYES FOR LEATHER, PAPER, AND NON-WOVEN TEXTILES | SANDOZ LTD. (CH) | 1978-03-21 | — | — | US | disclosed |