Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 14/20 | 0.44 |
| ▸ | SCN1A | P35498 | 2/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.36 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL938365 | 0.87 | SCN5A (0.46) | SCN5ASCN1ASCN2ASERPINE1 | |
| SCHEMBL15787103 | 0.79 | SCN5A (0.48) | SCN5ASCN1ASCN2ASERPINE1 | |
| SCHEMBL15787102 | 0.79 | SCN5A (0.48) | SCN5ASCN1ASCN2ASERPINE1 | |
| SCHEMBL938366 | 0.77 | SCN5A (0.46) | SCN5ASCN1ASCN2ASERPINE1 | |
| SCHEMBL939192 | 0.74 | SCN5A (0.48) | SCN5ASCN1ASCN2ASERPINE1GRK6 | |
| SCHEMBL937114 | 0.74 | SCN5A (0.46) | SCN5ASCN1ASCN2A | |
| SCHEMBL937112 | 0.74 | SCN5A (0.46) | SCN5ASCN1ASCN2A | |
| SCHEMBL937849 | 0.74 | SCN5A (0.58) | SCN5ASCN1ASCN2A | |
| SCHEMBL935933 | 0.73 | SCN5A (0.54) | SCN5ASCN1ASCN2A | |
| SCHEMBL12945164 | 0.72 | SCN5A (0.46) | SCN5ASCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011014462-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2011-02-03 | — | — | WO | claimed |