Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.57 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2908868 | 0.91 | SMN1; SMN2 (0.72) | SMN1; SMN2CYP19A1CYP17A1L3MBTL1GAA | |
| SCHEMBL11605250 | 0.88 | SMN1; SMN2 (0.74) | SMN1; SMN2CYP19A1CYP17A1L3MBTL1MAPT | |
| SCHEMBL11609783 | 0.88 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP19A1CYP17A1L3MBTL1LMNA | |
| SCHEMBL11614958 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP19A1CYP17A1L3MBTL1GAA | |
| SCHEMBL11611752 | 0.85 | SMN1; SMN2 (0.60) | SMN1; SMN2CYP17A1L3MBTL1GAATSHR | |
| SCHEMBL28016900 | 0.82 | SRD5A2 (0.59) | SRD5A2 | |
| SCHEMBL10966183 | 0.80 | SMN1; SMN2 (0.66) | SMN1; SMN2CYP17A1L3MBTL1MAPK1GAA | |
| SCHEMBL10965548 | 0.79 | SMN1; SMN2 (0.53) | SMN1; SMN2CYP19A1CYP17A1L3MBTL1GAA | |
| SCHEMBL10970695 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2CYP19A1CYP17A1MAPK1CYP3A4 | |
| SCHEMBL11732756 | 0.78 | SMN1; SMN2 (0.51) | SMN1; SMN2CYP17A1L3MBTL1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4098908-A | PHENOXYPHENYL PYRIDYL KETONES AND DERIVATIVES AND THEIR USE AS HYPOLEPIDEMIC AGENTS | SANDOZ, INC. (US) | 1978-07-04 | — | — | US | disclosed |