Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GSK3A | P49840 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11606563 | 0.81 | GSK3A (0.46) | NPC1RAB9AGSK3AGSK3BPTGS2 | |
| SCHEMBL11607156 | 0.79 | GSK3A (0.45) | NPC1RAB9AGSK3AGSK3BSMN1; SMN2 | |
| SCHEMBL11607976 | 0.79 | GSK3B (0.48) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL11606034 | 0.79 | GSK3A (0.50) | NPC1RAB9AGSK3AGSK3BALDH1A1 | |
| SCHEMBL11611982 | 0.77 | GSK3A (0.50) | GSK3AGSK3BPTGS2 | |
| SCHEMBL11608010 | 0.75 | GSK3A (0.44) | NPC1GSK3AGSK3BALDH1A1 | |
| SCHEMBL11606006 | 0.73 | TP53 (0.39) | ALDH1A1PTGS2PTGS1TP53 | |
| SCHEMBL11607018 | 0.72 | GSK3A (0.59) | GSK3AGSK3BALDH1A1 | |
| SCHEMBL11610697 | 0.71 | HSP90AA1 (0.44) | NPC1RAB9AALDH1A1 | |
| SCHEMBL11609123 | 0.70 | GSK3A (0.43) | NPC1RAB9AGSK3AGSK3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4087534-A | N-haloalkylmio urazole pesticides | OVADIA DAVID | 1978-05-02 | — | — | US | disclosed |