Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 14/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 6/20 | 0.53 |
| ▸ | RECQL | P46063 | 4/20 | 0.53 |
| ▸ | BLM | P54132 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.53 |
| ▸ | THPO | P40225 | 3/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11269487 | 0.86 | DRD1 (0.67) | DRD1KDM4EDRD2RECQLBLM | |
| SCHEMBL11609337 | 0.85 | DRD1 (0.56) | DRD1KDM4EDRD2RECQLBLM | |
| SCHEMBL11256897 | 0.85 | DRD1 (0.68) | DRD1KDM4EDRD2RECQLBLM | |
| SCHEMBL11606513 | 0.83 | DRD1 (0.76) | DRD1KDM4EDRD2RECQLBLM | |
| Bromide SCHEMBL11604921 | 0.82 | DRD1 (0.73) | DRD1KDM4EDRD2RECQLBLM | |
| SCHEMBL11606454 | 0.80 | DRD1 (0.39) | DRD1KDM4EDRD2RECQLBLM | |
| Bromide SCHEMBL11477045 | 0.80 | DRD1 (0.54) | DRD1KDM4EDRD2RECQLBLM | |
| SCHEMBL11606787 | 0.77 | ADCY5 (0.74) | DRD1KDM4EDRD2RECQLBLM | |
| Bromide SCHEMBL11609493 | 0.76 | ADCY5 (0.72) | DRD1KDM4EDRD2RECQLBLM | |
| Bromide SCHEMBL11612091 | 0.75 | KDM4E (0.72) | DRD1KDM4EDRD2RECQLBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4104379-A | DOPAMINERGIC ACTIVITY | SMITHKLINE CORPORATION (US) | 1978-08-01 | — | — | US | disclosed |