Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.62 |
| ▸ | F10 | P00742 | 19/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18897606 | 0.90 | F10 (0.76) | MAOBF10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1160965 | 0.90 | F10 (0.76) | MAOBF10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1160969 | 0.90 | F10 (0.76) | MAOBF10CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL19230362 | 0.77 | F10 (0.87) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL806189 | 0.77 | F10 (0.87) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL15319214 | 0.77 | F10 (0.75) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL18409562 | 0.76 | MAOB (1.00) | MAOBF10 | |
| SCHEMBL793664 | 0.76 | F10 (0.81) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL793663 | 0.76 | F10 (0.81) | F10CYP1A2CYP3A4CYP2D6CYP2C9 | |
| Hydrochloric Acid SCHEMBL793868 | 0.76 | F10 (0.73) | F10CYP1A2CYP3A4CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2459555-A1 | PROCESSES FOR CRYSTALLIZATION OF RIVAROXABAN | KRKA, D.D., Novo Mesto (SI) | 2012-06-06 | — | — | EP | disclosed |
| WO-2011012321-A1 | PROCESSES FOR CRYSTALLIZATION OF RIVAROXABAN | KRKA, D.D., NOVO MESTO (SI) | 2011-02-03 | — | — | WO | disclosed |