SCHEMBL1160997

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1160847	0.85	AURKA (0.53)	AURKAAURKBMST1RNPC1RAB9A
	SCHEMBL11032381	0.85	AURKA (0.60)	AURKAAURKBNPC1RAB9ADYRK3
	SCHEMBL1161339	0.83	MST1R (0.63)	AURKAAURKBMST1RNPC1RAB9A
	SCHEMBL11028078	0.83	AURKA (0.57)	AURKAAURKBMST1RNPC1RAB9A
	SCHEMBL1160856	0.82	AURKA (0.64)	AURKAAURKBMST1R
	SCHEMBL11031533	0.78	AURKA (0.56)	AURKAAURKB
	SCHEMBL11026897	0.78	PTGS1 (0.41)	NPC1RAB9ACLK2DYRK1ACLK4
	SCHEMBL11031640	0.77	AURKA (0.53)	AURKAAURKBNPC1RAB9ASMN1; SMN2
	SCHEMBL13273656	0.77	AURKA (1.00)	AURKAAURKB
	SCHEMBL11886912	0.76	AURKA (0.56)	AURKAAURKBNPC1RAB9AROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.