Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 7/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | DBH | P09172 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11615174 | 0.81 | IDO1 (0.53) | IDO1TAAR1MAOBMIFALDH1A1 | |
| SCHEMBL11613933 | 0.81 | IDO1 (0.44) | IDO1AGXTTAAR1MAOBMIF | |
| SCHEMBL11615168 | 0.81 | CYP3A4 (0.44) | IDO1AGXTTAAR1MAOBCHRM2 | |
| SCHEMBL11616310 | 0.79 | SLC6A2 (0.40) | IDO1TAAR1MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL11611424 | 0.77 | IDO1 (0.38) | IDO1AGXTTAAR1MAOBMIF | |
| SCHEMBL3647842 | 0.77 | TAAR1 (0.52) | IDO1AGXTTAAR1MAOBMIF | |
| SCHEMBL11515144 | 0.74 | TAAR1 (0.42) | IDO1AGXTTAAR1MAOBMIF | |
| SCHEMBL17288527 | 0.74 | CYP1A2 (0.44) | SLC6A3 | |
| SCHEMBL1044897 | 0.72 | TAAR1 (0.63) | IDO1AGXTTAAR1MAOBMIF | |
| SCHEMBL7766359 | 0.72 | TAAR1 (0.49) | IDO1AGXTTAAR1MAOBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122282-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-10-24 | — | — | US | disclosed |
| US-4099014-A | BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1978-07-04 | — | — | US | disclosed |
| US-4085139-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4081478-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-03-28 | — | — | US | disclosed |
| US-4073808-A | PROSTAGLANDINS | THE UPJOHN COMPANY (US) | 1978-02-14 | — | — | US | disclosed |
| US-4033989-A | 9-Deoxy-PGF2 Analogs | THE UPJOHN COMPANY (US) | 1977-07-05 | — | — | US | disclosed |
| US-4016184-A | PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS | THE UPJOHN COMPANY (US) | 1977-04-05 | — | — | US | disclosed |