Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.69 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.48 |
| ▸ | PTGFR | P43088 | 1/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.47 |
| ▸ | PPARD | Q03181 | 4/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | TLR2 | O60603 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11617329 | 0.93 | FFAR4 (0.74) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL11618654 | 0.92 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL11615881 | 0.92 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL11615905 | 0.92 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL7550732 | 0.92 | FFAR4 (0.77) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL11619689 | 0.90 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL11613838 | 0.90 | FFAR4 (0.75) | FFAR4FFAR1ALDH1A1FAAHGPR84 | |
| SCHEMBL1881604 | 0.89 | FFAR4 (0.85) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL1884346 | 0.89 | FFAR4 (0.85) | FFAR4FFAR1ALDH1A1GPR84PPARG | |
| SCHEMBL1301396 | 0.89 | FFAR4 (0.85) | FFAR4FFAR1ALDH1A1GPR84PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4097504-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-06-27 | — | — | US | disclosed |
| US-4092356-A | 11,12-Secoprostaglandins | MERCK & CO., INC. (US) | 1978-05-30 | — | — | US | disclosed |
| US-4066692-A | 11,12-SECOPROSTAGLANDINS | MERCK & CO., INC. (US) | 1978-01-03 | — | — | US | disclosed |