Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 12/20 | 0.82 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.77 |
| ▸ | NPC1 | O15118 | 2/20 | 0.77 |
| ▸ | RAB9A | P51151 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20379197 | 0.91 | NAMPT (1.00) | NAMPT | |
| SCHEMBL15574584 | 0.89 | NPC1 (0.72) | NAMPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL20388990 | 0.85 | NAMPT (1.00) | NAMPT | |
| SCHEMBL11617698 | 0.83 | NAMPT (0.82) | NAMPTNPC1RAB9AKMT2AHTT | |
| SCHEMBL11613865 | 0.83 | NAMPT (0.82) | NAMPTSMN1; SMN2RAB9AKMT2AHTT | |
| SCHEMBL20389120 | 0.83 | NAMPT (0.80) | NAMPT | |
| SCHEMBL20389041 | 0.83 | NAMPT (0.66) | NAMPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL11615122 | 0.83 | NAMPT (0.83) | NAMPTSMN1; SMN2NPC1RAB9AHTT | |
| SCHEMBL8212768 | 0.82 | NAMPT (0.84) | NAMPTSMN1; SMN2NPC1RAB9AKMT2A | |
| SCHEMBL20380323 | 0.82 | HTT (0.72) | NAMPTSMN1; SMN2NPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | claimed |