Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14984020 | 0.81 | MAPT (0.60) | MAPTL3MBTL1TDP1APPDRD2 | |
| SCHEMBL30514009 | 0.81 | MAPT (0.60) | MAPTL3MBTL1TDP1APPDRD2 | |
| SCHEMBL9808262 | 0.79 | MAPT (0.62) | MAPTL3MBTL1TDP1APPDRD2 | |
| SCHEMBL7617783 | 0.78 | PPARA (0.57) | MAPTPPARADRD2DRD4DRD3 | |
| SCHEMBL5660131 | 0.75 | MAPT (0.59) | MAPTL3MBTL1TDP1APPDRD2 | |
| SCHEMBL8434882 | 0.74 | CA12 (0.61) | MAPTL3MBTL1TDP1APPDRD2 | |
| SCHEMBL23128627 | 0.74 | NR5A1 (0.68) | MAPTL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL13042288 | 0.74 | NR5A1 (0.68) | MAPTL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL13110618 | 0.74 | NR5A1 (0.68) | MAPTL3MBTL1TDP1NPC1RAB9A | |
| SCHEMBL11983233 | 0.74 | NR5A1 (0.68) | MAPTL3MBTL1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4126623-A | BENZYL OR PHENYL ETHERS AND THIOETHERS WITH A LINEAR ALIPHATIC CHAIN HAVING A HALOGENATED END GROUP AND EXHIBITING JUVENILE HORMONE AND ACARICIDE ACTIVITY | MONTEDISON S.P.A. (IT) | 1978-11-21 | — | — | US | disclosed |