Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 8/20 | 0.59 |
| ▸ | LMNA | P02545 | 5/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | RAB9A | P51151 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11618093 | 0.86 | HTT (0.56) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11617882 | 0.86 | HTT (0.56) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL12599390 | 0.86 | HTT (0.63) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL3786921 | 0.83 | POLB (0.66) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL18620099 | 0.81 | HTT (0.62) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL11190347 | 0.81 | HTT (0.59) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL14379237 | 0.79 | HTT (0.65) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL10892309 | 0.79 | HTT (0.68) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL10818236 | 0.79 | HTT (0.59) | HTTLMNAPOLBNPC1RAB9A | |
| SCHEMBL8350034 | 0.77 | POLB (0.68) | HTTLMNAPOLBNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092148-A | HERBICIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1978-05-30 | — | — | US | disclosed |