Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832315 | 0.89 | KDM4E (0.55) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL30203380 | 0.88 | KDM4E (0.54) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL31509765 | 0.88 | KDM4E (0.54) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL23844744 | 0.88 | KDM4E (0.54) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL8839197 | 0.86 | HTT (0.47) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL29066902 | 0.84 | KDM4E (0.50) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL4686604 | 0.83 | HTT (0.44) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL4680106 | 0.83 | FOLH1 (0.45) | TP53KDM4EMEN1RECQLKMT2A | |
| SCHEMBL31558666 | 0.83 | CYP4F2 (0.47) | TP53MEN1KMT2ACYP2C9CYP4F2 | |
| Phthalic Acid SCHEMBL28439156 | 0.81 | TSHR (0.53) | KDM4EMEN1RECQLKMT2ACYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127666-A | ANTIEMETIC | UNIVERSITE D'ORLEANS (FR) | 1978-11-28 | — | — | US | disclosed |