Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14382477 | 0.87 | KDM4E (0.68) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL2058958 | 0.87 | SMN1; SMN2 (0.59) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL8487851 | 0.84 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL7176813 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29905006 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL28224179 | 0.81 | SMN1; SMN2 (0.49) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL27459370 | 0.81 | SMN1; SMN2 (0.49) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL24073765 | 0.79 | KDM4E (0.49) | KDM4EALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL1315833 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10KMT2A | |
| SCHEMBL29760302 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1HPGDHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4127666-A | ANTIEMETIC | UNIVERSITE D'ORLEANS (FR) | 1978-11-28 | — | — | US | disclosed |