SCHEMBL11615625

SCHEMBL11615625

O=C(O)CNc1ccno1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.49
TP53 P04637 1/20 0.38
RAB9A P51151 1/20 0.38
CDC25A P30304 1/20 0.37
PTGDR2 Q9Y5Y4 1/20 0.35
PTGS2 P35354 1/20 0.34
MAPT P10636 1/20 0.33
EGLN2 Q96KS0 1/20 0.33
FTO Q9C0B1 1/20 0.33
HDAC1 Q13547 1/20 0.33
MME P08473 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22130289 0.74
SCHEMBL5154431 0.72
SCHEMBL280374 0.72 KMT2A (0.42) TAAR1RAB9AMEN1KMT2AALDH1A1
SCHEMBL22862335 0.71 TAAR1 (0.76) TAAR1TP53RAB9AHDAC1MEN1
SCHEMBL2140847 0.69 FABP1 (0.47) TAAR1MAPTMEN1KMT2AALDH1A1
SCHEMBL13798845 0.68
SCHEMBL669647 0.68
Hydrochloric Acid SCHEMBL11086564 0.67 CYP2C19 (0.43) RAB9ACDC25AMAPTKMT2AALDH1A1
SCHEMBL3685770 0.67 CYP2C19 (0.43) RAB9ACDC25AMAPTKMT2AALDH1A1
Malonic Acid SCHEMBL28946708 0.67 TAAR1 (0.42) TAAR1PTGDR2MAPTHDAC1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4088816-A BACTERICIDES E. R. SQUIBB & SONS, INC. (US) 1978-05-09 US disclosed