Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.63 |
| ▸ | NR4A2 | P43354 | 6/20 | 0.62 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MITF | O75030 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11418944 | 0.91 | NPC1 (0.76) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL5533836 | 0.90 | NPC1 (0.80) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11616376 | 0.89 | NPC1 (0.63) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL2486400 | 0.87 | NR4A2 (0.82) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11613581 | 0.87 | NR4A2 (0.77) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11413840 | 0.86 | NPC1 (0.85) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11617747 | 0.86 | NPC1 (0.80) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11406007 | 0.86 | NPC1 (0.85) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11616811 | 0.80 | NPC1 (0.74) | NPC1RAB9ACASP3SENP8SENP7 | |
| SCHEMBL11406672 | 0.79 | NPC1 (0.80) | NPC1RAB9ACASP3SENP8SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086421-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1978-04-25 | — | — | US | disclosed |
| US-4049813-A | HYPOLIPIDEMIC AGENTS | SANDOZ, INC. (US) | 1977-09-20 | — | — | US | disclosed |