Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10298178 | 1.00 | CYP1A2 (0.57) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL6379710 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL6379708 | 0.83 | CYP1A2 (0.57) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL10298184 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL10298185 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL17708537 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL28775033 | 0.79 | GRIN1 (0.61) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL14377747 | 0.79 | CYP19A1 (0.42) | CYP1A2CYP2D6HSD17B10LMNAL3MBTL1 | |
| SCHEMBL7118034 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 | |
| SCHEMBL7118032 | 0.79 | CYP1A2 (0.53) | CYP1A2CYP2D6HSD17B10LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4118378-A | THIURAM SULFIDES OF OXAZOLIDINES AND THIAZOLIDINES | PENNWALT CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |
| US-4099003-A | NON-BLOOMING ACCELERATOR AND PROCESS FOR VULCANIZATION OF EPDM ELASTOMERS | PENNWALT CORPORATION (US) | 1978-07-04 | — | — | US | disclosed |