Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.77 |
| ▸ | NAMPT | P43490 | 8/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | NPC1 | O15118 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.61 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.61 |
| ▸ | KDR | P35968 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29635847 | 0.87 | NAMPT (1.00) | NAMPT | |
| SCHEMBL165336 | 0.87 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379352 | 0.86 | NAMPT (0.85) | SMN1; SMN2L3MBTL1NAMPTMEN1KMT2A | |
| SCHEMBL11616056 | 0.86 | NAMPT (0.74) | SMN1; SMN2NAMPTLMNAMEN1KMT2A | |
| SCHEMBL11646536 | 0.86 | MAPT (0.73) | L3MBTL1NAMPTLMNAMEN1KMT2A | |
| SCHEMBL23447441 | 0.85 | MAPT (0.71) | SMN1; SMN2L3MBTL1LMNARAB9AMEN1 | |
| SCHEMBL165841 | 0.84 | NAMPT (1.00) | NAMPT | |
| SCHEMBL9191959 | 0.83 | KMT2A (0.71) | NPC1TSHRRAB9AMEN1KMT2A | |
| SCHEMBL12335395 | 0.83 | NAMPT (0.66) | SMN1; SMN2L3MBTL1NAMPTLMNAMEN1 | |
| SCHEMBL18315964 | 0.83 | NAMPT (0.72) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4088766-A | PRODUCTION OF PROSTAGLANDINS IN MAMMALS | THE UPJOHN COMPANY (US) | 1978-05-09 | — | — | US | claimed |