Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MOK | Q9UQ07 | 9/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 3/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620655 | 0.92 | CNR2 (0.46) | MOKL3MBTL1CNR2CYP2A13 | |
| SCHEMBL11618263 | 0.87 | KDM4E (0.49) | MOKL3MBTL1ALDH1A1HTTALOX15 | |
| SCHEMBL11616315 | 0.86 | KDM4E (0.51) | MOKL3MBTL1NPC1ALDH1A1HTT | |
| SCHEMBL14995431 | 0.81 | MOK (0.48) | MOKCNR2 | |
| SCHEMBL11616547 | 0.80 | KDM4E (0.45) | MOKALDH1A1ALOX15KDM4E | |
| SCHEMBL11620424 | 0.78 | KDM4E (0.47) | MOKL3MBTL1NPC1ALDH1A1ALOX15 | |
| SCHEMBL11617455 | 0.78 | KDM4E (0.47) | MOKL3MBTL1NPC1ALDH1A1ALOX15 | |
| SCHEMBL11619722 | 0.77 | GAA (0.48) | ALOX15 | |
| SCHEMBL11624529 | 0.74 | CNR2 (0.48) | MOKCNR2 | |
| SCHEMBL18491364 | 0.73 | MOK (0.55) | MOKCNR2ALDH1A1HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101671-A | ANTIULCEROGENICS | BOEHRINGER INGELHEIM GMBH (DE) | 1978-07-18 | — | — | US | disclosed |
| US-RE29628-E | ANTIULCER, SECRETOLYTICS, ANTITUSSIVE | BOEHRINGER INGELHEIM GMBH (DT) | 1978-05-09 | — | — | US | disclosed |
| US-3950393-A | ANTIULCER, ANTISECRETORY, ANTITUSSIVE AGENTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-04-13 | — | — | US | disclosed |