Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ROS1 | P08922 | 1/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11622275 | 0.90 | PDE5A (0.33) | KDM4ES1PR4GPBAR1MAP4K1AGPAT2 | |
| SCHEMBL11624559 | 0.90 | CNR1 (0.42) | KDM4EHPGDCNR1ALPLCNR2 | |
| SCHEMBL11618395 | 0.89 | GPBAR1 (0.35) | KDM4EGAAGPBAR1LRRK2CNR1 | |
| SCHEMBL11622693 | 0.85 | GPBAR1 (0.40) | GPBAR1CYP3A4 | |
| SCHEMBL11621036 | 0.83 | CDC7 (0.34) | KDM4EPTGDR2HTTCNR1ALPL | |
| SCHEMBL11622924 | 0.82 | CNR1 (0.39) | KDM4EHTTGPBAR1CYP3A4CNR1 | |
| SCHEMBL11621505 | 0.81 | RIPK2 (0.44) | — | |
| SCHEMBL11624566 | 0.81 | CNR2 (0.42) | GPBAR1CNR1CNR2 | |
| SCHEMBL11621394 | 0.79 | KDM4E (0.35) | KDM4EPTGDR2HPGDGAAGPBAR1 | |
| SCHEMBL11624694 | 0.79 | TSHR (0.37) | KDM4EHTTGAAGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | claimed |
| US-4072498-A | HERBICIDES | THE UPJOHN COMPANY (US) | 1978-02-07 | — | — | US | disclosed |