Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | USP14 | P54578 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11626968 | 0.87 | NOTUM (0.66) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL11629032 | 0.84 | NOTUM (0.55) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL11625228 | 0.83 | MAPK1 (0.54) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL28017620 | 0.80 | NOTUM (0.74) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL11377279 | 0.73 | NOTUM (0.56) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL11624685 | 0.72 | NOTUM (0.68) | NOTUMALDH1A1POLBMAPTGAA | |
| SCHEMBL11626756 | 0.72 | NOTUM (0.63) | NOTUMALDH1A1POLBSMN1; SMN2MAPK1 | |
| SCHEMBL1980763 | 0.72 | NOTUM (1.00) | NOTUMALDH1A1SMN1; SMN2MAPK1MAPT | |
| SCHEMBL11623203 | 0.72 | NOTUM (0.66) | NOTUMALDH1A1POLBSMN1; SMN2MAPT | |
| SCHEMBL29868078 | 0.71 | MAPT (0.38) | ALDH1A1POLBSMN1; SMN2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115101-A | PLANT GROWTH REGULATORS, CHEMICAL HYBRIDIZATION AGENTS | ROHM AND HAAS COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4051142-A | PLANT GROWTH REGULATORS | ROHM AND HAAS COMPANY (US) | 1977-09-27 | — | — | US | disclosed |