Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11608399 | 0.85 | CYP3A4 (0.46) | CYP19A1CYP3A4CYP3A5RAB9AALDH1A1 | |
| SCHEMBL16230653 | 0.85 | CYP19A1 (0.56) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL30927957 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP3A5RAB9AKMT2A | |
| SCHEMBL29226497 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP3A5RAB9AKMT2A | |
| SCHEMBL29226492 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP3A5RAB9AKMT2A | |
| SCHEMBL30927949 | 0.84 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP3A5RAB9AKMT2A | |
| SCHEMBL16230682 | 0.84 | KCNA5 (0.53) | CYP19A1CYP3A4CYP3A5KDM4E | |
| SCHEMBL11153024 | 0.83 | CYP19A1 (0.54) | CYP19A1CYP3A4ALDH1A1 | |
| SCHEMBL4473850 | 0.83 | CYP19A1 (0.64) | CYP19A1CYP3A4CYP3A5RAB9A | |
| SCHEMBL11629744 | 0.83 | CYP19A1 (0.70) | CYP19A1CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |