Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | GRM2 | Q14416 | 5/20 | 0.41 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | NAAA | Q02083 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11627603 | 1.00 | HDAC3 (0.48) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL17490747 | 0.81 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL18951461 | 0.78 | HDAC3 (0.41) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11620270 | 0.77 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11630095 | 0.77 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11627772 | 0.77 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11619925 | 0.77 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11624008 | 0.77 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11622320 | 0.77 | HDAC3 (0.42) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL11621575 | 0.77 | HDAC3 (0.44) | HDAC3HDAC1HDAC2HDAC10HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4092327-A | Preparation of isoxazolines | TEXACO INC. (US) | 1978-05-30 | — | — | US | disclosed |