Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 6/20 | 0.50 |
| ▸ | GCK | P35557 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11628746 | 0.88 | MAPK1 (0.44) | PDE5AGCKMAPK1HTTXDH | |
| SCHEMBL11625206 | 0.86 | HTT (0.54) | PDE5AMAPK1HTTPTGES | |
| SCHEMBL11630723 | 0.85 | PDE5A (0.47) | PDE5AGCKMAPK1XDHGUSB | |
| SCHEMBL11625024 | 0.84 | PDE5A (0.56) | PDE5AMAPK1GUSB | |
| SCHEMBL11628419 | 0.81 | PDE5A (0.56) | PDE5AALOX15HSD17B10 | |
| SCHEMBL11626841 | 0.81 | PDE5A (0.52) | PDE5AALOX15 | |
| SCHEMBL11628099 | 0.79 | PDE5A (0.46) | PDE5AXDHGUSB | |
| SCHEMBL11626668 | 0.78 | PDE5A (0.49) | PDE5AXDHGUSB | |
| SCHEMBL11629185 | 0.78 | PDE5A (0.42) | PDE5AMAPK1HTTPTGESGUSB | |
| SCHEMBL11708696 | 0.78 | PDE5A (0.51) | PDE5AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4082751-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-04-04 | — | — | US | disclosed |