Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7263581 | 0.81 | ATM (0.65) | TDP1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL259981 | 0.81 | TDP1 (0.52) | TDP1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL12846059 | 0.81 | TDP1 (0.56) | TDP1POLBRAB9ANPC1LMNA | |
| SCHEMBL9558612 | 0.80 | TDP1 (0.63) | TDP1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL7271626 | 0.79 | POLB (0.54) | TDP1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL351615 | 0.79 | — | — | |
| SCHEMBL7262989 | 0.79 | ATM (0.57) | TDP1POLBRAB9ANPC1LMNA | |
| SCHEMBL10288965 | 0.78 | TDP1 (0.53) | TDP1POLBRAB9ANPC1LMNA | |
| Hydrochloric Acid SCHEMBL8437714 | 0.77 | AKR1B1 (0.48) | TDP1POLBRAB9ANPC1L3MBTL1 | |
| SCHEMBL28636520 | 0.77 | AKR1B1 (0.48) | TDP1POLBRAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4086423-A | CEPHALOSPORINS, CYCLOADDITION OF GLYCINE DERIVATIVE TO THIAZINE COMPOUND | MERCK & CO., INC. (US) | 1978-04-25 | — | — | US | disclosed |