SCHEMBL11632004

SCHEMBL11632004

OC1COC(c2ccccc2F)OC1

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 3/20 0.41
KDM1B Q8NB78 1/20 0.41
HTR2C P28335 2/20 0.40
HTR2B P41595 2/20 0.40
GAA P10253 2/20 0.40
KDM4E B2RXH2 1/20 0.40
CYP19A1 P11511 1/20 0.38
RCOR1 Q9UKL0 1/20 0.33
KMT2A Q03164 2/20 0.33
PKM P14618 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MEN1 O00255 1/20 0.33
MAOB P27338 2/20 0.32
MAOA P21397 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8251752 0.79 KDM1A (0.47) KDM1AKDM1BHTR2CHTR2BGAA
SCHEMBL11635434 0.77 KMT2A (0.44) KDM1AHTR2CHTR2BRCOR1KMT2A
SCHEMBL29655183 0.77 TAAR1 (0.41) HTR2CHTR2BKMT2AMEN1MAOB
SCHEMBL11632118 0.77 HTR2C (0.41) KDM1AHTR2CHTR2BGAARCOR1
SCHEMBL13610515 0.76 KDM1A (0.44) KDM1AKDM1BHTR2CHTR2BGAA
SCHEMBL11631932 0.74 CARM1 (0.43) KDM1AKDM1BHTR2CHTR2BKMT2A
SCHEMBL11631937 0.74 CARM1 (0.43) KDM1AKDM1BHTR2CHTR2BKMT2A
SCHEMBL11629567 0.73 HTR2C (0.44) HTR2CHTR2BCYP19A1KMT2ACA1
SCHEMBL937009 0.73 KDM1A (0.48) KDM1AKDM1BHTR2CHTR2BGAA
SCHEMBL29749063 0.73 KDM1A (0.48) KDM1AKDM1BHTR2CHTR2BGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed