Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.64 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | CYP3A5 | P20815 | 3/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10442614 | 0.87 | CFTR (0.54) | CYP19A1CYP3A4CFTRSLC6A2SLC6A4 | |
| SCHEMBL10442149 | 0.85 | CFTR (0.59) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17069272 | 0.85 | CFTR (0.59) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5018916 | 0.84 | CFTR (0.44) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4047293 | 0.83 | CFTR (0.43) | CYP19A1CFTRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18675614 | 0.79 | TSHR (0.50) | CYP19A1CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18675613 | 0.79 | TSHR (0.50) | CYP19A1CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL683676 | 0.79 | TSHR (0.50) | CYP19A1CYP3A4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL683625 | 0.79 | TSHR (0.59) | CYP19A1FFAR2CYP3A4SLC6A2SLC6A4 | |
| SCHEMBL10674497 | 0.78 | CYP19A1 (1.00) | CYP19A1CYP3A4CYP3A5CFTRSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4116665-A | Method of regulating the growth of aquatic weeds with pyridine derivatives | ELI LILLY AND COMPANY (US) | 1978-09-26 | — | — | US | disclosed |